Quickly obtain sections as slender or thick as your software calls for, with no worrying about losing or distorting valuable tissue samples.
Our switch-important SmartBatch+ system brings together electrophoretic tissue clearing and immunolabeling into 1 superior-throughput system.
Antibodies may well consider months to diffuse via just a few millimeters of tissue, having a steep labeling gradient from floor to core.
Megatome is created for precision: the blade vibrates at a greater frequency and bigger amplitude selection than other microtomes, and features a exceptional deflection Handle system.
SE employs a rotational electrical area to disperse hugely electromobile molecules (for instance antibodies or surfactant micelles) all over a porous sample devoid of detrimental electrically charged structures within the tissue. This allows two-4 day clearing of intact organs,
Our preformulated EasyIndex Option raises and homogenize the refractive index of delipidated tissue samples, rendering them entirely transparent. This enables light-weight penetration in the sample and makes certain the acquisition of significant-resolution, in-emphasis picture data.
Megatome is actually a novel microtome that allows for top-precision sectioning of an array megatomi.com of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with small tissue harm and knowledge reduction.
eFLASH is a swift tissue labeling approach which allows for uniform entire-organ staining in 20 rounds of labeling.
The SmartSPIM light-weight sheet microscope offers unparalleled resolution and acquisition velocity during intact tissue volumes, though its modular design and style allows you to up grade and customize particular person elements.
Docset generation requires at minimal two alternatives: the identify from the docset and The situation from the Javadoc documents to include inside the docset.
This will create a docset named Sample in The existing directory. Docset development is usually customized with optional arguments:
Protect avoids the variability of hydrogel embedding and the information loss from PFA preservation, defending specimens for numerous rounds of processing.
--displayName: Will set the title as demonstrated in Sprint. This is useful in case you make a docset with name SampleProject but Show name Sample Undertaking rather. This placing will default to the worth of --identify if omitted.
Our novel Defend tissue preservation procedure sorts intramolecular bonds applying polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.